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Heterocyclic chemistry is a branch of organic chemistry that deals with the synthesis, properties and applications of these heterocycles. Compounds classified as heterocyclic are probably the largest and most diverse family of organic compounds. Heterocyclic chemistry studies particularly focus on unsaturated derivatives and unstrained 5- and 6-membered rings are involved in the predominance of the work and application. Pyridine, thiophen, pyrrol, and furan are included. In Chemistry, a macrocyclic ligand is a macrocycle with at fewer than nine ring sizes and three or more locations with donors, including all hetero-atoms. Crown ethers and porphyrins are popular examples. Particularly strong affinity for metal ions exhibits macrocyclic ligands.
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